<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">najo</journal-id><journal-title-group><journal-title xml:lang="en">Nanosystems: Physics, Chemistry, Mathematics</journal-title><trans-title-group xml:lang="ru"><trans-title>Наносистемы: физика, химия, математика</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2220-8054</issn><issn pub-type="epub">2305-7971</issn><publisher><publisher-name>Университет ИТМО</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">najo-1013</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>Synthesis and study of nanosized biomaterials based on hydroxyapatite</article-title><trans-title-group xml:lang="ru"><trans-title></trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="western" xml:lang="en"><surname>Bogdanova</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="en"><p>Ekaterinburg</p></bio><email xlink:type="simple">chemi4@rambler.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="western" xml:lang="en"><surname>Sabirzyanov</surname><given-names>N. A.</given-names></name></name-alternatives><bio xml:lang="en"><p>Ekaterinburg</p></bio><email xlink:type="simple">sabirzyanov@ihim.uran.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="en" id="aff-1"><institution>Institute of Solid State Chemistry, Ural Branch of the Russian Academy of Science</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2014</year></pub-date><pub-date pub-type="epub"><day>15</day><month>08</month><year>2025</year></pub-date><volume>5</volume><issue>4</issue><fpage>590</fpage><lpage>596</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Bogdanova E.A., Sabirzyanov N.A., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Bogdanova E.A., Sabirzyanov N.A.</copyright-holder><copyright-holder xml:lang="en">Bogdanova E.A., Sabirzyanov N.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://nanojournal.ifmo.ru/jour/article/view/1013">https://nanojournal.ifmo.ru/jour/article/view/1013</self-uri><abstract><p>Directed synthesis of ﬂuorine- and silicon-containing apatites was carried out. The limiting degrees of substitution of silicate groups for phosphate groups were proposed. The physico-chemical properties of the produced materials were investigated.</p></abstract><kwd-group xml:lang="en"><kwd>biomaterials</kwd><kwd>fluorine-substituted hydroxyapatite</kwd><kwd>silicon-substituted hydroxyapatite</kwd></kwd-group><funding-group><funding-statement xml:lang="en">This work was supported by the Presidium of the Ural Branch of RAS (program No. 12-P-3-1003).</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Guelcher S.A., Hollinger J.O. An introduction to biomaterials. New York: CRC Press, 2006.</mixed-citation><mixed-citation xml:lang="en">Guelcher S.A., Hollinger J.O. An introduction to biomaterials. New York: CRC Press, 2006.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Darimont G.L., Gilbert B., Cloots R. Non-destructive evaluation of crystallinity and chemical composition by raman spectroscopy in hydroxyapatite-coated implants. Mater Lett., 58, P. 71–73 (2003).</mixed-citation><mixed-citation xml:lang="en">Darimont G.L., Gilbert B., Cloots R. Non-destructive evaluation of crystallinity and chemical composition by raman spectroscopy in hydroxyapatite-coated implants. Mater Lett., 58, P. 71–73 (2003).</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Cheng K., Weng W., Qu H., Du P., Shen G., Han G., Yang J., Ferreira J.M.F. J. Biomed. Matter. Res. Part B, Appl. Biomater., B.69, P. 33 (2004).</mixed-citation><mixed-citation xml:lang="en">Cheng K., Weng W., Qu H., Du P., Shen G., Han G., Yang J., Ferreira J.M.F. J. Biomed. Matter. Res. Part B, Appl. Biomater., B.69, P. 33 (2004).</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Zeng H., Chittur K.K., Laceﬁeld W.R. Biomaterials, 20, P. 377 (1999).</mixed-citation><mixed-citation xml:lang="en">Zeng H., Chittur K.K., Laceﬁeld W.R. Biomaterials, 20, P. 377 (1999).</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Zhang S., Zeng X.T., Wang Y.S., Cheng K., Weng W. Adhesion strength of sol-gel derived ﬂuoridated hydroxyapatite coatings. Surf Coat Technol., 200, P. 6350–6354 (2006).</mixed-citation><mixed-citation xml:lang="en">Zhang S., Zeng X.T., Wang Y.S., Cheng K., Weng W. Adhesion strength of sol-gel derived ﬂuoridated hydroxyapatite coatings. Surf Coat Technol., 200, P. 6350–6354 (2006).</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Lee E.J., Lee S.H., Kim H.W., Kong Y.M., Kim H.E. Fluoridated apatite coatings on titanium obtained by electron-beam deposition. Biomaterials, 26, P. 3843–3851 (2005).</mixed-citation><mixed-citation xml:lang="en">Lee E.J., Lee S.H., Kim H.W., Kong Y.M., Kim H.E. Fluoridated apatite coatings on titanium obtained by electron-beam deposition. Biomaterials, 26, P. 3843–3851 (2005).</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Gibson I. R., Bests. M., Bonﬁeld W. Chemical characterization of silicon-substituted hydroxyapatite. J. Biomed. Mater. Res., 44, P. 422 (1999).</mixed-citation><mixed-citation xml:lang="en">Gibson I. R., Bests. M., Bonﬁeld W. Chemical characterization of silicon-substituted hydroxyapatite. J. Biomed. Mater. Res., 44, P. 422 (1999).</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Patel N., Best S.M., Bonﬁeld W. J. Mater. Sci. Mater. Med., 13, P. 1199–1206 (2002).</mixed-citation><mixed-citation xml:lang="en">Patel N., Best S.M., Bonﬁeld W. J. Mater. Sci. Mater. Med., 13, P. 1199–1206 (2002).</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Kim S.R., Lee J.H., Kim Y.T., Riu D.H., Jung S.J., Lee Y.J., Chung S.C., Kim Y.H. Synthesis of Si, Mg substituted hydroxyapatites and their sintering behaviors. Biomaterials, 24(8), P. 1389–1398 (2003).</mixed-citation><mixed-citation xml:lang="en">Kim S.R., Lee J.H., Kim Y.T., Riu D.H., Jung S.J., Lee Y.J., Chung S.C., Kim Y.H. Synthesis of Si, Mg substituted hydroxyapatites and their sintering behaviors. Biomaterials, 24(8), P. 1389–1398 (2003).</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Bonel G. Contribution al etude de la carbonation des apatites. Ann.Chim., 7(3), P. 127–144 (1972).</mixed-citation><mixed-citation xml:lang="en">Bonel G. Contribution al etude de la carbonation des apatites. Ann.Chim., 7(3), P. 127–144 (1972).</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Putlayev V., Veresov A., Pulkin M., Soin A., Kuznetsov V. Silicon-substituted hydroxyapatite ceramics (Si-HAp): densiﬁcation and grain growth through the prism of sintering theories. Mat.-Wiss.Werkstoﬀtech., 37(6), P. 416–421 (2006).</mixed-citation><mixed-citation xml:lang="en">Putlayev V., Veresov A., Pulkin M., Soin A., Kuznetsov V. Silicon-substituted hydroxyapatite ceramics (Si-HAp): densiﬁcation and grain growth through the prism of sintering theories. Mat.-Wiss.Werkstoﬀtech., 37(6), P. 416–421 (2006).</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Pietak A.M., Reid J.W., Stott M.J., Sayer M. Silicon substitution in the calcium phosphate bioceramics. Biomaterials, 28, P. 4023–4032 (2007).</mixed-citation><mixed-citation xml:lang="en">Pietak A.M., Reid J.W., Stott M.J., Sayer M. Silicon substitution in the calcium phosphate bioceramics. Biomaterials, 28, P. 4023–4032 (2007).</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
