najoNanosystems: Physics, Chemistry, MathematicsНаносистемы: физика, химия, математика2220-80542305-7971Университет ИТМО10.17586/2220-8054-2018-9-3-389-400najo-812Research ArticleCHEMISTRY AND MATERIAL SCIENCEХИМИЯ И МАТЕРИАЛОВЕДЕНИЕStudy of glucose concentration influence on blood optical properties in THz frequency rangeGusevS. I.

Kronverkskiy Ave, 49, St. Petersburg, 197101

mail@gusev-spb.ruDemchenkoP. S.

Kronverkskiy Ave, 49, St. Petersburg, 197101

LitvinovE. A.

Kronverkskiy Ave, 49, St. Petersburg, 197101

CherkasovaO. P.

Ac. Lavrentiev Ave, 13, Novosibirsk, 630090

K. Marksa Ave, 20, Novosibirsk, 630073

MeglinskiI. V.

P.O. Box 4500, FI-90015, Oulu

KhodzitskyM. K.

Kronverkskiy Ave, 49, St. Petersburg, 197101

khodzitskiy@yandex.ruTerahertz Biomedicine laboratory, ITMO UniversityRussian FederationBiophysics laboratory, Institute of Laser Physics of SB RAS; Novosibirsk State Technical UniversityRussian FederationUniversity of OuluFinland20181408202593389400Copyright © Gusev S.I., Demchenko P.S., Litvinov E.A., Cherkasova O.P., Meglinski I.V., Khodzitsky M.K., 20252025Gusev S.I., Demchenko P.S., Litvinov E.A., Cherkasova O.P., Meglinski I.V., Khodzitsky M.K.Gusev S.I., Demchenko P.S., Litvinov E.A., Cherkasova O.P., Meglinski I.V., Khodzitsky M.K.This work is licensed under a Creative Commons Attribution 4.0 License.https://nanojournal.ifmo.ru/jour/article/view/812

The optical properties of whole human blood with the different glucose level were studied by terahertz time-domain spectroscopy at frequencies ranging from 0.3 – 0.5 THz. The increasing of refractive index of blood at the glucose level growth was shown for series of experiments. The dispersion of complex refractive index of human nails was obtained. Based on these data, the non-invasive glucose measuring technique was proposed which utilizes the reflection of the THz pulse from nail plate/nail bed interface.

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The authors declare that there are no conflicts of interest present.