Magnet-induced behavior of iron carbide (Fe7C3@C) nanoparticles in the cytoplasm of living cells
https://doi.org/10.17586/2220-8054-2016-7-1-158-160
Аннотация
The uptake of superparamagnetic Fe7C3@C nanoparticles into living cells and their behavior once inside the cell was investigated. The cells used were shown to absorb the nanoparticle aggregates over the first 30 minutes. After absorption, these aggregates moved towards the center of the cell and accumulated near the cell nucleus. No toxic effects on cell physiology were observed. In a magnetic field, the particles aligned in the cells along magnetic lines and shifted to the magnet’s side. During long-term cultivation, Fe7C3@C nanoparticle aggregates were ultimately discarded via exocytosis.
Ключевые слова
Об авторах
I. Alieva
Belozersky Institute of Physico-Chemical Biology, Moscow State University
Россия
Россия
Moscow
I. Kireev
Belozersky Institute of Physico-Chemical Biology, Moscow State University
Россия
Россия
Moscow
A. Rakhmanina
L.F. Vereshchagin Institute for High Pressure Physics of the RAS
Россия
Россия
Troitsk
A. Garanina
Belozersky Institute of Physico-Chemical Biology, Moscow State University
Россия
Россия
Moscow
O. Strelkova
Belozersky Institute of Physico-Chemical Biology, Moscow State University
Россия
Россия
Moscow
O. Zhironkina
Belozersky Institute of Physico-Chemical Biology, Moscow State University
Россия
Россия
Moscow
V. Cherepaninets
Belozersky Institute of Physico-Chemical Biology, Moscow State University
Россия
Россия
Moscow
V. Davydov
L.F. Vereshchagin Institute for High Pressure Physics of the RAS
Россия
Россия
Troitsk
V. Khabashesku
Center for Technology Innovation, Baker Hughes Inc.
Соединённые Штаты Америки
Соединённые Штаты Америки
Houston, TX, 77040
V. Agafonov
GREMAN, UMR CNRS 7347, Université François Rabelais
Франция
Франция
37200 Tours
R. Uzbekov
Faculté de Médecine, Université François Rabelais; Faculty of Bioengineering and Bioinformatics, Moscow State University
Россия
Россия
Tours; Moscow
Список литературы
1. Davydov V., Rakhmanina A., Kireev I., Alieva I., Zhironkina O., Strelkova O., Dianova V., Samani T.D., Mireles M., Hocine Yahia L., Uzbekov R., Agafonov V., Khabashesku V. Solid state synthesis of carbon-encapsulated iron carbide nanoparticles and their interaction with living cells. J. Mater. Chem. B, 2014, 2, P. 4250–4261.
2. Uzbekov R.E., Kireev I.I., Alieva I.B., Davydov V. A., Rakhmanina A.V., Agafonov V. Interaction of Iron Carbide Nanoparticles protected by Carbon Shell Onion-like Structure with living Cells. Joint Intern. Conf. “Advanced Carbon Nanostructures” (ACNS’ 2013) St. Petersburg, Russia.
Рецензия
Для цитирования:
Alieva I., Kireev I., Rakhmanina A., Garanina A., Strelkova O., Zhironkina O., Cherepaninets V., Davydov V., Khabashesku V., Agafonov V., Uzbekov R. Magnet-induced behavior of iron carbide (Fe7C3@C) nanoparticles in the cytoplasm of living cells. Наносистемы: физика, химия, математика. 2016;7(1):158-160. https://doi.org/10.17586/2220-8054-2016-7-1-158-160
For citation:
Alieva I., Kireev I., Rakhmanina A., Garanina A., Strelkova O., Zhironkina O., Cherepaninets V., Davydov V., Khabashesku V., Agafonov V., Uzbekov R. Magnet-induced behavior of iron carbide (Fe7C3@C) nanoparticles in the cytoplasm of living cells. Nanosystems: Physics, Chemistry, Mathematics. 2016;7(1):158-160. https://doi.org/10.17586/2220-8054-2016-7-1-158-160
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