Effect of periodic permeability of lung airways on the flow dynamics of viscous fluid
https://doi.org/10.17586/2220-8054-2019-10-3-235-242
Abstract
In this study, we aimed to find the effect of periodic permeability on the flow dynamics of an incompressible, Newtonian, viscous and pulsatile flow of air flowing through airway generations 5–10. To solve this problem, we used a generalized Navier Stokes equation by including the Darcy law of a porous media with periodic permeability for the flow of air and Newton equation of motion for the flow of nanoparticles. The finite difference explicit numerical scheme has been carried out to solve the governing nonlinear equations and then computational work is done on MATLAB R2016 by user defined code. After performing numerical computation we found by varying mean permeability of porous media velocity of air and particle increased gradually with axial and radial distance respectively.
About the Authors
J. KoriIndia
Roorkee-247667, Uttarakhand
. Pratibha
India
Roorkee-247667, Uttarakhand
References
1. Heyder J. Deposition of Inhaled Particles in the Human Respiratory Tract and Consequences for Regional Targeting in Respiratory Drug Delivery. Proc Am Thorac Soc., 2004, P. 315-320.
2. Kori J., Pratibha. Numerical Simulation of Dusty Air Flow and Particle Deposition Inside Permeable Alveolar Duct. Int. J. Appl. Comput. Math, 2019, 5, P. 1–13.
3. Tian L., Shang Y., Chen R., Bai R., Chen C., Inthavong K., Tu1 J. A combined experimental and numerical study on upper airway dosimetry of inhaled nanoparticles from an electrical discharge machine shop. Particle and Fibre Toxicology, 2017, 14, P. 24.
4. Li D., Xu Q., Liu Y., Libao Y., Jun J. Numerical Simulation of Particles Deposition in a Human Upper Airway. Advances in Mechanical Engineering, 2014.
5. Sturm R. Theoretical deposition of carcinogenic particle aggregates in the upper respiratory tract. Ann Transl Med., 2013, 1, P. 25.
6. Sturm R. A computer model for the simulation of nanoparticle deposition in the alveolar structures of the human lungs. Ann Transl Med., 2015, 3, P. 281.
7. Saini A., Katiyar V.K., Pratibha. Two-dimensional model of nanoparticle deposition in the alveolar ducts of the human lung. Applications & Applied Mathematics, 2017, 12, P. 305–318.
8. Haber S., Yitzhak D., Tsuda A. Gravitational deposition in a rhythmically expanding and contracting alveolus. J. Appl. Physiol., 2013, 95, P. 657–671.
9. DeGroot C.T., Straatman A.G. A porous media model of alveolar duct flow in the human lung. Journal of Porous Media, 2018.
10. Khanafer K., Cook K., Marafie A. The Role of Porous Media in Modeling Fluid Flow Within Hollow Fiber Membranes of The Total Artificial Lung. J. Porous Media, 2012, 15, P. 113–122.
11. Cheng P. Heat Transfer in Geothermal Systems. Advances in Heat Transfer, 1979, 14, P. 1–105.
12. Vafai K., Tien C.L. Boundary and Inertia Effects on Flow and Heat Transfer in Porous Media. Int. J. Heat Mass Transfer, 1981, 24, P. 195–203.
13. Kuwahara F., Sano Y., Liu J., Nakayama A. A Porous Media Approach for Bifurcating Flow and Mass Transfer in a Human Lung. J. Heat Transfer, 2009, 131, P. 101013-5.
14. Saini A., Katiyar V.K., Pratibha. Numerical simulation of gas flow through a biofilter in lung tissues. World Journal of Modelling and Simulation, 2015, 11, P. 33–42.
15. Balashazy I., Hofmann W., Farkas A.,, Madas B.G. Three-dimensional model for aerosol transport and deposition in expanding and contracting alveoli. Inhalation Toxicology, 2008, 20, P. 611–621.
16. Sturm R., Hofmann W. A theoretical approach to the deposition and clearance of fibers with variable size in the human respiratory tract. J. of Hazardous Materials, 2009, 170, P. 210–218.
17. Darcy H. Les Fontaines Publiques de la Ville de Dijon. Dalmont, Paris, 1856.
18. Singh K.D., Verma G.N. Three-Dimensional Oscillatory Flow through a Porous Medium with Periodic Permeability. Z. Angew. Math. Mech., 1995, 75, P. 599–604.
19. Kori J., Pratibha. Numerical Simulation of Mucus Clearance inside Lung Airways. Journal of Applied Fluid Mechanics, 2018, 11, P. 1163– 1171.
20. Kori J., Pratibha. Simulation and Modeling for Aging and Particle Shape Effect on Airflow Dynamics and Filtration Efficiency of Human Lung, Journal of Applied Fluid Mechanics, 2019, 12, P. 1273–1285.
21. Smith S., Cheng U.S., Yeh H.C. Deposition of ultrafine particles in human tracheobronchial airways of adults and children. Aerosol Sci. Tech., 2010, 35, P. 697–709.
22. Seraa T., Uesugib K., Yagib N., Yokotac H. Numerical simulation of airflow and microparticle deposition in a synchrotron micro-CT-based pulmonary acinus model. Computer Methods in Biomechanics and Biomedical Engineering, 2013, 18, P. 1427-1435.
23. Koullapis P.G., Kassinos S.C., Bivolarova M.P., Melikov A.K. Particle deposition in a realistic geometry of the human conducting airways: Effects of inlet velocity profile, inhalation flowrate and electrostatic charge. J Biomech., 2016, 49(11), P. 2201–2212.
24. Ismail Z., Abdullah I., Mustapha N., Amin N. A power-law model of blood flow through a tapered overlapping stenosed artery. Appl. Math. Comput., 2007, 195, P. 669–680.
25. Kapur J.N. Mathematical Models in Biology and Medicine. East-West Press, Pvt. Ltd., New Delhi, 1985.
26. Mandal P.K. An unsteady analysis of non-Newtonian blood flow through tapered arteries with a stenosis. Int. J. Non-Linear Mech., 2005, 40, P. 151–164.
27. Singh P., Misra J.K., Narayan K.A. Free convection along a vertical wall in a porous medium with periodic permeability variation. Int. J. Numer. Anal. Methods Geomech., 1989, 13.
Review
For citations:
Kori J., Pratibha Effect of periodic permeability of lung airways on the flow dynamics of viscous fluid. Nanosystems: Physics, Chemistry, Mathematics. 2019;10(3):235-242. (In Russ.) https://doi.org/10.17586/2220-8054-2019-10-3-235-242