Biological effect of zirconium dioxide-based nanoparticles
https://doi.org/10.17586/2220-8054-2017-8-3-391-396
Abstract
This work demonstrates the positive effects of zirconium dioxide nanoparticles on cells in vitro. This is supported by the absence of toxicity, stimulation of metabolic and proliferative activity. The nanoparticles of solid solution of europium oxide in europium dioxide do not exhibit an explicit biological effect. The potentially successful application of zirconium dioxide-based nanoparticles in pharmacology has been demonstrated.
Keywords
zirconium dioxide,
europium oxide,
nanoparticles,
toxicity,
metabolic activity,
proliferative activity
Supporting agencies: The authors express their gratitude to V. V. Gusarov for the attention he paid to the work and for his help in the interpretation of the results. The work has been performed with the financial support offered by Russian Science Foundation (Project No. 16-13-10252).
About the Authors
O. V. Almjasheva
1St. Petersburg Electrotechnical University “LETI”
Russian Federation
Russian Federation
ul. Professora Popova 5, 197376 St. Petersburg
A. V. Garabadzhiu
St. Petersburg State Technological Institute (Technical university)
Russian Federation
Russian Federation
Moskovsky prospect 26, 190013 St. Petersburg
Yu. V. Kozina
St. Petersburg State Technological Institute (Technical university)
Russian Federation
Russian Federation
Moskovsky prospect 26, 190013 St. Petersburg
L. F Litvinchuk
State Research Institute of Highly Pure Biopreparations of the Federal Medical Biological Agency FMB
Russian Federation
Russian Federation
Pudozhskaya ul. 7, 197110 St. Petersburg
V. P. Dobritsa
State Research Institute of Highly Pure Biopreparations of the Federal Medical Biological Agency FMB
Russian Federation
Russian Federation
Pudozhskaya ul. 7, 197110 St. Petersburg
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Review
For citations:
Almjasheva O.V., Garabadzhiu A.V., Kozina Yu.V., Litvinchuk L.F., Dobritsa V.P. Biological effect of zirconium dioxide-based nanoparticles. Nanosystems: Physics, Chemistry, Mathematics. 2017;8(3):391-396. https://doi.org/10.17586/2220-8054-2017-8-3-391-396
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