Cerium dioxide nanoparticles as third-generation enzymes (nanozymes)
https://doi.org/10.17586/2220-8054-2017-8-6-760-781
Abstract
Ceria nanoparticles are capable of performing the function of some enzymes (such as oxidoreductases, phosphatase) and can be classified as nanozymes. In this review, the actual data on the enzymatic activity of ceria were critically analyzed and specific conditions under which the cerium dioxide nanoparticles can act as enzymes were defined. The presented analysis may be useful in the planning, design and synthesis of ceria nanoparticles having the desired enzymatic functions required for various processes, including the development of the nanodrugs, which exhibit the therapeutic effect depending on their composition and pH of media, development of molecular sensors and biosensors, etc.
Supporting agencies: This research has been supported by the Russian Science Foundation (project 17-73-10417).
About the Authors
A. L. Popov
Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences
Russian Federation
Russian Federation
Pushchino, Moscow region, 142290
A. B. Shcherbakov
Zabolotny Institute of Microbiology and Virology, National Academy of Sciences of Ukraine
Ukraine
Ukraine
Kyiv D0368
N. M. Zholobak
Zabolotny Institute of Microbiology and Virology, National Academy of Sciences of Ukraine
Ukraine
Ukraine
Kyiv D0368
A. Ye. Baranchikov
Kurnakov Institute of General and Inorganic Chemistry of Russian Academy of Sciences
Russian Federation
Russian Federation
Moscow 119991
V. K. Ivanov
Kurnakov Institute of General and Inorganic Chemistry of Russian Academy of Sciences
Russian Federation
Russian Federation
Moscow 119991
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For citations:
Popov A.L., Shcherbakov A.B., Zholobak N.M., Baranchikov A.Ye., Ivanov V.K. Cerium dioxide nanoparticles as third-generation enzymes (nanozymes). Nanosystems: Physics, Chemistry, Mathematics. 2017;8(6):760-781. https://doi.org/10.17586/2220-8054-2017-8-6-760-781
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