Study of glucose concentration influence on blood optical properties in THz frequency range
https://doi.org/10.17586/2220-8054-2018-9-3-389-400
Abstract
The optical properties of whole human blood with the different glucose level were studied by terahertz time-domain spectroscopy at frequencies ranging from 0.3 – 0.5 THz. The increasing of refractive index of blood at the glucose level growth was shown for series of experiments. The dispersion of complex refractive index of human nails was obtained. Based on these data, the non-invasive glucose measuring technique was proposed which utilizes the reflection of the THz pulse from nail plate/nail bed interface.
Supporting agencies: This work was financially supported by the Government of Russian Federation, Grant 074-U01.
About the Authors
S. I. Gusev
Terahertz Biomedicine laboratory, ITMO University
Russian Federation
Russian Federation
Kronverkskiy Ave, 49, St. Petersburg, 197101
P. S. Demchenko
Terahertz Biomedicine laboratory, ITMO University
Russian Federation
Russian Federation
Kronverkskiy Ave, 49, St. Petersburg, 197101
E. A. Litvinov
Terahertz Biomedicine laboratory, ITMO University
Russian Federation
Russian Federation
Kronverkskiy Ave, 49, St. Petersburg, 197101
O. P. Cherkasova
Biophysics laboratory, Institute of Laser Physics of SB RAS; Novosibirsk State Technical University
Russian Federation
Russian Federation
Ac. Lavrentiev Ave, 13, Novosibirsk, 630090
K. Marksa Ave, 20, Novosibirsk, 630073
I. V. Meglinski
University of Oulu
Finland
Finland
P.O. Box 4500, FI-90015, Oulu
M. K. Khodzitsky
Terahertz Biomedicine laboratory, ITMO University
Russian Federation
Russian Federation
Kronverkskiy Ave, 49, St. Petersburg, 197101
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Review
For citations:
Gusev S.I., Demchenko P.S., Litvinov E.A., Cherkasova O.P., Meglinski I.V., Khodzitsky M.K. Study of glucose concentration influence on blood optical properties in THz frequency range. Nanosystems: Physics, Chemistry, Mathematics. 2018;9(3):389-400. https://doi.org/10.17586/2220-8054-2018-9-3-389-400
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