NANOSYSTEMS: PHYSICS, CHEMISTRY, MATHEMATICS, 2013, 4 (1), P. 72-77
THE NANOCRYSTALLINE CERIUM DIOXIDE RAISES THE FUNCTIONAL ACTIVITY OF GENESIAL SYSTEM OF AGEING MALES OF RATS
N.Ya. Spivak – D. K. Zabolotny Institute of Microbiology and Virology of the National Academy of Sciences of Ukraine, Kyiv, Ukraine; “DiaProphMed”Ltd, Kyiv, Ukraine
N. D. Nosenko – V. P. Komissarenko Institute of Endocrinology and Metabolism of National Academy of Medical Sciences of Ukraine, Kyiv, Ukraine
N. M. Zholobak – D. K. Zabolotny Institute of Microbiology and Virology of the National Academy of Sciences of Ukraine, Kyiv, Ukraine
A. B. Shcherbakov – D. K. Zabolotny Institute of Microbiology and Virology of the National Academy of Sciences of Ukraine, Kyiv, Ukraine
A. G. Reznikov – V. P. Komissarenko Institute of Endocrinology and Metabolism of National Academy of Medical Sciences of Ukraine, Kyiv, Ukraine
O. S. Ivanova – N. S. Kurnakov Institute of General and Inorganic Chemistry of the Russian Academy of Sciences, Moscow, Russia
V. K. Ivanov – N. S. Kurnakov Institute of General and Inorganic Chemistry of the Russian Academy of Sciences, Moscow, Russia; Department of Materials Science, M.V. Lomonosov Moscow State University, Moscow, Russia
Yu. D. Tretyakov – N. S. Kurnakov Institute of General and Inorganic Chemistry of the Russian Academy of Sciences, Moscow, Russia; Department of Materials Science, M.V. Lomonosov Moscow State University, Moscow, Russia
Effect of a nanocrystalline cerium dioxide (nanoceria) on the reproductive system of elderly male rats has been studied. It was shown that nanoceria administration (1 mg/kg for 10 days) considerably increases testosterone level, quantity of spermatozoa and quantity of rat cubs in the litter born by pubertal intact females. Physical and sexual development of rat cubs in the test group did not differ from the control.
Keywords: ananocrystalline cerium dioxide, male rats, testosterone, spermatozoa.
UDC 546.655.4-31 + 599.323.41 : 591.139 : 591.463 : 612.063 : 4.09
PACS 87.85.Rs
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